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Integrating biocatalysis into organic synthesis • EDITORIAL |
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Thermostable carboxylesterases from
hyperthermophiles • REVIEW ARTICLE |
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Hydantoin-hydrolysing enzymes for the enantioselective production
of amino acids: new insights and applications • REVIEW ARTICLE |
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Engineering lipase B from Candida antarctica • REVIEW ARTICLE |
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‘Low-temperature method’ for a dramatic improvement in
enantioselectivity in lipase-catalyzed reactions • REVIEW ARTICLE |
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Challenges in the development of an efficient enzymatic
process in the pharmaceutical industry • REVIEW
ARTICLE |
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Rational strategies for highly enantioselective
lipase-catalyzed kinetic resolutions of very bulky chiral compounds:
substrate design and high-temperature biocatalysis • REVIEW ARTICLE |
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Stereoselective oxidations and reductions catalyzed by
nonredox proteins • REVIEW ARTICLE |
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Catalytic diversity of fatty acid desaturases • REVIEW ARTICLE |
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Synthetic applications of tryptophan synthase • REVIEW ARTICLE |
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Chemoenzymatic approaches to the dynamic kinetic
asymmetric synthesis of aromatic amino acids • SHORT COMMUNICATION |
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Enzymatic resolution of (RS)-2-(1-aminoethyl)-3-chloro-5-(substituted)pyridines • SHORT COMMUNICATION |
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Enzymatic transformations. Part 58: Enantioconvergent
biohydrolysis of styrene oxide derivatives catalysed by the Solanum
tuberosum epoxide hydrolase •
SHORT
COMMUNICATION |
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Facile biocatalytic syntheses of optically active 4-hydroxycyclohex-2-enone
and 4-benzylthiacyclopent-2-enone
• SHORT
COMMUNICATION |
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Enzyme assisted syntheses of chiral building blocks for
isosters of diglycerides, phospholipids and PAF • SHORT COMMUNICATION |
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Realization of the synthesis of |
,
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Mannosidase chemistry of the mannopeptimycin
complex • SHORT COMMUNICATION |
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Regio and enantioselective reduction of t-butyl
6-chloro-3,5-dioxohexanoate with baker’s yeast • SHORT COMMUNICATION |
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Rapid identification of cytochrome P450cam
variants by in vivo screening of active site libraries • SHORT COMMUNICATION |
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Enzymatic oxidation of thioanisoles: isolation and
absolute configuration of metabolites • SHORT
COMMUNICATION |
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Asymmetric reduction of 2-chloroacrylic acid to (S)-2-chloropropionic
acid by a novel reductase from Burkholderia sp. WS • SHORT COMMUNICATION |
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Enzymatic synthesis of N-methyl-L-phenylalanine by
a novel enzyme, N-methyl-L-amino acid dehydrogenase, from Pseudomonas
putida • SHORT COMMUNICATION |
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In situ enzymatic screening (ISES) of P,N-ligands for
Ni(0)-mediated asymmetric intramolecular allylic amination • SHORT COMMUNICATION |
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Enzymatic desymmetrization/resolution of epoxydiols
derived from 1,4-naphthoquinone, 5-hydroxy-1,4-naphthoquinone and
5,8-dihydroxy-1,4-naphthoquinone
• ARTICLE |
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Synthesis and resolution of a key building block for
epothilones: a comparison of asymmetric synthesis, chemical and enzymatic
resolution • ARTICLE |
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Lipase-catalyzed highly enantioselective kinetic
resolution of racemic α-hydroxy butenolides • ARTICLE |
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Advanced procedure for the enzymatic ring opening of unsaturated
alicyclic |
-lactams
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Regioselective enzymatic syntheses of C-3 and C-5
carbonate A-ring stereoisomeric precursors of vitamin D • ARTICLE |
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Efficient chemoenzymatic enantioselective synthesis of
diacylglycerols (DAG) • ARTICLE |
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Lipase-catalysed kinetic resolution of 1-O-alkylglycerols
by sequential transesterification
• ARTICLE |
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An ‘easy-on, easy-off’ protecting group for the
enzymatic resolution of (±)-1-phenylethylamine in an aqueous medium • ARTICLE |
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Enantiopure building blocks for the synthesis of
3-methyl-2-alkanols. Diastereoselective methylmetal addition to a chiral
2-methylaldehyde followed by lipase catalysed esterification • ARTICLE |
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Enantioselective esterification of (RS)-2-(4-chlorophenoxy)propionic
acid via Carica papaya lipase in organic solvents • ARTICLE |
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Enzyme assisted enantioselective synthesis of the
alkaloid (+)-aloperine • ARTICLE |
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Laccase-mediated oxidation of the steroid hormone
17β-estradiol in organic solvents
• ARTICLE |
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An enzymatic process to α-ketoglutarate from
L-glutamate: the coupled system L-glutamate dehydrogenase/NADH oxidase • ARTICLE |
|
Hydrogen peroxide-producing NADH oxidase (nox-1) from Lactococcus
lactis • ARTICLE |
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Enantioselective epoxidation of chalcone catalysed by
the artificial enzyme poly-L-leucine: kinetic mechanism • ARTICLE |
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A straightforward synthesis of an aminocyclitol based on
an enzymatic aldol reaction and a highly stereoselective intramolecular Henry
reaction • ARTICLE |
|
Immobilization of benzaldehyde lyase and its
application as a heterogeneous catalyst in the continuous synthesis of a
chiral 2-hydroxy ketone • ARTICLE |
|
The first hydroxynitrile lyase catalysed cyanohydrin formation
in ionic liquids • ARTICLE |
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Microbial deracemization of α-substituted carboxylic
acids: control of the reaction path
• ARTICLE |
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Highly enantioselective recombinant thermoalkalophilic
lipases from Geobacillus and Bacillus sp • ARTICLE |
|
Universal chromogenic substrates for lipases and
esterases • ARTICLE |
|
Mapping the substrate selectivity and enantioselectivity
of esterases from thermophiles • ARTICLE |
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Parallel synthesis of an ester library for substrate
mapping of esterases and lipases
• ARTICLE |
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Editorial board • EDITORIAL
BOARD |
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Graphical contents list • CONTENTS LIST |
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Contributors to this issue • INDEX |
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Stereochemistry abstracts • ABSTRACT |
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Tetrahedron: Asymmetry reports • LITERATURE |
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Instructions to contributors • PUBLISHER'S NOTE |
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Cumulative author index • INDEX |
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Copyright © 2004 Elsevier B.V. All rights reserved. ScienceDirect® is a registered trademark of Elsevier B.V. |